IL11 antibody

• Background:

  Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (PubMed:2145578) . Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation (PubMed:12919066) . Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3.

• Synonyms:

  Interleukin-11 (IL-11) |Adipogenesis inhibitory factor (AGIF) |IL11

• Gene ID:

  3589

• UniProt:

  P20809

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Interleukin 11

• Target:

  IL11

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB

• Field of Research:

  Immunology, Cardiovascular

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:200-1:1000

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  25 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB

• Immunogen Sequence:

  22-199aa