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IL11 antibody

CAT: 0710-FNab04216Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab04216Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (PubMed:2145578) . Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation (PubMed:12919066) . Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3.
Synonyms
Interleukin-11 (IL-11) |Adipogenesis inhibitory factor (AGIF) |IL11
Gene ID
3589
UniProt
P20809
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Interleukin 11
Target
IL11
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Immunology, Cardiovascular
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:1000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
25 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB
Immunogen Sequence
22-199aa

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