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ERCC3 antibody

CAT: 0710-FNab02834Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab02834Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes an ATP-dependent DNA helicase that functions in nucleotide excision repair. The encoded protein is a subunit of basal transcription factor 2 (TFIIH) and, therefore, also functions in class II transcription. Mutations in this gene are associated with Xeroderma pigmentosum B, Cockayne's syndrome, and trichothiodystrophy. Alternative splicing results in multiple transcript variants.
Synonyms
General transcription and DNA repair factor IIH helicase subunit XPB (TFIIH subunit XPB) |Basic transcription factor 2 89 kDa subunit (BTF2 p89) |DNA excision repair protein ERCC-3|DNA repair protein complementing XP-B cells|TFIIH basal transcription factor complex 89 kDa subunit (TFIIH 89 kDa subunit, TFIIH p89) |Xeroderma pigmentosum group B-complementing protein|ERCC3|XPB|XPBC
Gene ID
2071
UniProt
P19447
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing)
Target
ERCC3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, WB
Field of Research
Epigenetics, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
80 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC, WB

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