ERCC3 antibody

• Background :

  This gene encodes an ATP-dependent DNA helicase that functions in nucleotide excision repair. The encoded protein is a subunit of basal transcription factor 2 (TFIIH) and, therefore, also functions in class II transcription. Mutations in this gene are associated with Xeroderma pigmentosum B, Cockayne's syndrome, and trichothiodystrophy. Alternative splicing results in multiple transcript variants.

• Synonyms :

  General transcription and DNA repair factor IIH helicase subunit XPB (TFIIH subunit XPB) |Basic transcription factor 2 89 kDa subunit (BTF2 p89) |DNA excision repair protein ERCC-3|DNA repair protein complementing XP-B cells|TFIIH basal transcription factor complex 89 kDa subunit (TFIIH 89 kDa subunit, TFIIH p89) |Xeroderma pigmentosum group B-complementing protein|ERCC3|XPB|XPBC

• Gene ID :

  2071

• UniProt :

  P19447

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  Excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing)

• Target :

  ERCC3

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, IHC, WB

• Field of Research :

  Epigenetics, Metabolism

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  80 kDa

• Shipping Conditions :

  4°C with ice bag

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, IHC, WB