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EIF3B antibody

CAT: 0710-FNab02702Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab02702Size:100 µg
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Background
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC) . The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. (Microbial infection) In case of FCV infection, plays a role in the ribosomal termination-reinitiation event leading to the translation of VP2 (PubMed:18056426) .
Synonyms
Eukaryotic translation initiation factor 3 subunit B (eIF3b) |Eukaryotic translation initiation factor 3 subunit 9|Prt1 homolog (hPrt1) |eIF-3-eta|eIF3 p110|eIF3 p116|EIF3B|EIF3S9
Gene ID
8662
UniProt
P55884
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Eukaryotic translation initiation factor 3, subunit B
Target
EIF3B
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
120 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

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