EIF3I antibody

• Background:

  Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC) . The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.

• Synonyms:

  Eukaryotic translation initiation factor 3 subunit I (eIF3i) |Eukaryotic translation initiation factor 3 subunit 2|TGF-beta receptor-interacting protein 1 (TRIP-1) |eIF-3-beta|eIF3 p36|EIF3I|EIF3S2|TRIP1

• Gene ID:

  8668

• UniProt:

  Q13347

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Eukaryotic translation initiation factor 3, subunit I

• Target:

  EIF3I

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, IHC, IF, IP, WB, FC

• Field of Research:

  Metabolism

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  36 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, IHC, IF, IP, WB, FC