RegisterLogin

EIF3E antibody

CAT: 0710-FNab02707Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab02707Size:100 µg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC) . The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. Required for nonsense-mediated mRNA decay (NMD) ; may act in conjunction with UPF2 to divert mRNAs from translation to the NMD pathway. May interact with MCM7 and EPAS1 and regulate the proteasome-mediated degradation of these proteins.
Synonyms
Eukaryotic translation initiation factor 3 subunit E (eIF3e) |Eukaryotic translation initiation factor 3 subunit 6|Viral integration site protein INT-6 homolog|eIF-3 p48|EIF3E|EIF3S6|INT6
Gene ID
3646
UniProt
P60228
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Eukaryotic translation initiation factor 3, subunit E
Target
EIF3E
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
48-52kd
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF

Related Products

CatalogName
FNab02712EIF3K antibody
FNab02702EIF3B antibody
FNab02709EIF3H antibody
FNab02711EIF3J antibody
FNab10356EIF4E antibody
FNab02713EIF3L antibody
FNab01323EIF4E antibody
FNab02708EIF3G antibody
FNab02704EIF3D antibody
FNab02705EIF3D antibody

Alternative Products

CatalogName
abx141750-01EIF3E (eIF3E) Antibody
C49470-01EIF3E Antibody

Popular Products