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CASP12 antibody

CAT: 0710-FNab01286Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab01286Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Caspase 12 is an enzyme known as a cysteine protease. It belongs to a family of enzymes called caspases that cleave their substrates at C-terminal aspartic acid residues. It is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. Caspase-12 is located in the endoplasmic reticulum (ER) . It is responsible for ER-stress-induced apoptosis, such as high calcium concentration, low oxygen and low glucose levels. This antibody detects endogenous levels of full-length caspase-12 protein (50 kDa) and its cleaved product (40-44 kDa) .
Synonyms
Inactive caspase-12 (CASP-12) |CASP12
UniProt
Q6UXS9
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Caspase 12 (gene/pseudogene)
Target
CASP12
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IF, IHC, WB, IP
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:10-1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
36-42 kDa, 50 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IF, IHC, WB, IP

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