CASP2 antibody
CAT:
710-FNab01287
Size:
100 µg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
CASP2 antibody
- Background: This gene encodes a member of the cysteine-aspartic acid protease(caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
- Synonyms: Caspase-2 (CASP-2)|Neural precursor cell expressed developmentally down-regulated protein 2 (NEDD-2)|Protease ICH-1|Caspase-2 subunit p18|Caspase-2 subunit p13|Caspase-2 subunit p12|CASP2|ICH1|NEDD2
- CAS Number: 9007-83-4
- UniProt: P42575
- Host: Rabbit
- Reactivity: Human, Mouse
- Immunogen: caspase 2, apoptosis-related cysteine peptidase
- Target: CASP2
- Clonality: Polyclonal
- Isotype: IgG
- Applications: ELISA, WB, IHC
- Field of Research: Metabolism
- Purification: Immunogen affinity purified
- Dilution: WB: 1:500-1:2000; IHC: 1:50-1:200
- Purity: ≥95% as determined by SDS-PAGE
- Form: Liquid
- Molecular Weight: 50 kDa
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)