CASP2 antibody

• Background :

  CASP2 (Caspase-2) is also named as ICH1, NEDD2 and belongs to the peptidase C14A family.It is involved in the activation cascade of caspases responsible for apoptosis execution and might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.It has 2 isoforms produced by alternative splicing and can exists almost as a dimer in solution (PMID:15865942) .This antibody can recognize the 32 kDa pro-caspase 2 as well as 18 kDa cleaved-caspase 2.

• Synonyms :

  Caspase-2 (CASP-2) |Neural precursor cell expressed developmentally down-regulated protein 2 (NEDD-2) |Protease ICH-1|Caspase-2 subunit p18|Caspase-2 subunit p13|Caspase-2 subunit p12|CASP2|ICH1|NEDD2

• Gene ID :

  835

• UniProt :

  P42575

• Host :

  Mouse

• Reactivity :

  Human

• Immunogen :

  Caspase 2

• Target :

  CASP2

• Clonality :

  Monoclonal

• Isotype :

  IgG1

• Applications :

  ELISA, WB

• Field of Research :

  Neuroscience, Immunology, Signal Transduction

• Purification :

  Protein A+G purification

• Dilution :

  WB: 1:1000-1:6000

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  18, 32, 50 kDa

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Clone ID :

  2B10

• Tested Applications :

  ELISA, WB