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MNI-caged-NMDA

CAT: 0804-HY-107717Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-107717Size:1 Each
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Description
MNI-caged-NMDA is a light-sensitive amino acid with rapid release properties suitable for use in the study of fast synaptic receptor mechanisms. MNI-caged-NMDA shows metered release of NMDA receptors, inducing rapid and sustained receptor activation in cerebellar interneurons. MNI-caged-NMDA is able to achieve rapid transient responses and generate large inward currents by local laser photolysis. The use of MNI-caged-NMDA can effectively study neurotransmitter signaling and its inhibitory effects on GABA-A receptors[1].
CAS Number
1227675-52-6
UNSPSC
12352005
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/mni-caged-nmda.html
Smiles
O=C(O)[C@H](NC)CC(N1CCC2=C1C([N+]([O-])=O)=CC=C2OC)=O
Molecular Formula
C14H17N3O6
Molecular Weight
323.30
References & Citations
[1]New caged neurotransmitter analogs selective for glutamate receptor sub-types based on methoxynitroindoline and nitrophenylethoxycarbonyl caging groups
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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