MBL-IN-3

MBL-IN-3

• CAS Number: 1452395-68-4
• UNSPSC Description: MBL-IN-3 (compound 72922413) is a New Delhi metallo-β-lactamase-1 (NDM-1) inhibitor(IC50=54±4 μM). MBL-IN-3 is identified and shown to lower minimum inhibitory concentrations (MICs) of Meropenem (HY-13678) for a panel of E. coli and K. pneumoniae clinical isolates expressing NDM-1. MBL-IN-3 can be used for antibiotic sensitizer research[1].
• Target Antigen: Bacterial
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-immunoregulation
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/mbl-in-3.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1C(C(N(CC2)CCC32C(O)CCCO3)=O)=CN=C4N1C=CC=C4O
• Molecular Weight: 359.38
• References & Citations: [1]Cheng Z, et al. Machine Learning Models Identify Inhibitors of New Delhi Metallo-β-lactamase[J]. Journal of Chemical Information and Modeling, 2024.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported