MBL-IN-3

• UNSPSC Description:

  MBL-IN-3 (compound 72922413) is a New Delhi metallo-β-lactamase-1 (NDM-1) inhibitor(IC50=54±4 μM). MBL-IN-3 is identified and shown to lower minimum inhibitory concentrations (MICs) of Meropenem (HY-13678) for a panel of E. coli and K. pneumoniae clinical isolates expressing NDM-1. MBL-IN-3 can be used for antibiotic sensitizer research[1].

• Target Antigen:

  Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/mbl-in-3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1C(C(N(CC2)CCC32C(O)CCCO3)=O)=CN=C4N1C=CC=C4O

• Molecular Weight:

  359.38

• References & Citations:

  [1]Cheng Z, et al. Machine Learning Models Identify Inhibitors of New Delhi Metallo-β-lactamase[J]. Journal of Chemical Information and Modeling, 2024.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1452395-68-4