MBL-IN-2

• UNSPSC Description:

  MBL-IN-2 ((2R, 2R')-5αC) is an inhibitor of Metallo-β-lactamase (MBL) that can inhibit New Delhi Metallo-β-lactamase-1 (NDM-1) with an IC50 of 0.3 μM. MBL-IN-2 ((2R, 2R')-5αC) can be used for the study of resistance to β-lactam antibiotics[1].

• Target Antigen:

  Bacterial; Beta-lactamase

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/mbl-in-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  SC[C@@H](C(F)(F)F)C(N1CCC[C@@H]1C(O)=O)=O

• Molecular Weight:

  271.26

• References & Citations:

  [1]Kondratieva A, et al. Fluorinated captopril analogues inhibit metallo-β-lactamases and facilitate structure determination of NDM-1 binding pose[J]. European Journal of Medicinal Chemistry, 2024: 116140.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported