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MBL-IN-2

CAT: 0804-HY-162174Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-162174Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MBL-IN-2 ((2R, 2R') -5αC) is an inhibitor of Metallo-β-lactamase (MBL) that can inhibit New Delhi Metallo-β-lactamase-1 (NDM-1) with an IC50 of 0.3 μM. MBL-IN-2 ((2R, 2R') -5αC) can be used for the study of resistance to β-lactam antibiotics[1].
UNSPSC
12352005
Target
Bacterial; Beta-lactamase
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/mbl-in-2.html
Solubility
10 mM in DMSO
Smiles
SC[C@@H](C(F)(F)F)C(N1CCC[C@@H]1C(O)=O)=O
Molecular Formula
C9H12F3NO3S
Molecular Weight
271.26
References & Citations
[1]Kondratieva A, et al. Fluorinated captopril analogues inhibit metallo-β-lactamases and facilitate structure determination of NDM-1 binding pose[J]. European Journal of Medicinal Chemistry, 2024: 116140.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported