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UKH-1114

CAT: 0804-HY-117731-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-117731-01Size:5 mg
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Description
UKH-1114 is a potent σ2 receptor/Tmem97 agonist with a Ki value of 46 nM, showing antimechanical hypersensitivity effects. UKH-1114 alleviates mechanical hypersensitivity caused by nerve injury without any movement disorders in mice. UKH-1114 is promising for research of neuropathic pain[1].
CAS Number
[2113664-14-3]
UNSPSC
12352005
Target
Sigma Receptor
Type
Reference compound
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ukh-1114.html
Purity
98.61
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OCCCN1CCCC2C3=CC=C(C4=CC=C(C(F)(F)F)C=C4)C=C3C1C2
Molecular Formula
C22H24F3NO
Molecular Weight
375.43
References & Citations
[1]Sahn JJ, et al. Sigma 2 Receptor/Tmem97 Agonists Produce Long Lasting Antineuropathic Pain Effects in Mice. ACS Chem Neurosci. 2017 Aug 16;8 (8) :1801-1811.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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