UKH-1114

• Target:

  Sigma receptor

• Related Pathways:

  GPCR/G Protein

• Bioactivity:

  UKH-1114 is a potent ?2 receptor/Tmem97 agonist with a Ki value of 46 nM, demonstrating antinociceptive effects against mechanical hypersensitivity. This compound alleviates mechanical hypersensitivity in mice caused by nerve injury without inducing motor impairment and is a promising candidate for neuropathic pain research.

• Smiles:

  FC (F) (F) C1=CC=C (C=C1) C=2C=CC3=C (C2) C4N (CCCO) CCCC3C4

• Molecular Formula:

  C22H24F3NO

• Molecular Weight:

  375.43

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2113664-14-3