UKH-1114

• Target :

  Sigma receptor

• Related Pathways :

  GPCR/G Protein

• Bioactivity :

  UKH-1114 is a potent ?2 receptor/Tmem97 agonist with a Ki value of 46 nM, demonstrating antinociceptive effects against mechanical hypersensitivity. This compound alleviates mechanical hypersensitivity in mice caused by nerve injury without inducing motor impairment and is a promising candidate for neuropathic pain research.

• Smiles :

  FC(F)(F)C1=CC=C(C=C1)C=2C=CC3=C(C2)C4N(CCCO)CCCC3C4

• Molecular Formula :

  C22H24F3NO

• Molecular Weight :

  375.43

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2113664-14-3