Products for Research Use Only
RegisterLogin

Ilaprazole (sodium)

CAT: 0804-HY-B2145-01Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-B2145-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Ilaprazole (IY-81149) sodium is an orally active proton pump inhibitor. Ilaprazole sodium irreversibly inhibits H+/K+-ATPase in a dose-dependent manner with an IC50 of 6 μM in rabbit parietal cell preparation. Ilaprazole sodium is used for the research of gastric ulcers. Ilaprazole sodium is also a potent TOPK (T-lymphokine-activated killer cell-originated protein kinase) inhibitor[1][2].
CAS Number
172152-50-0
Product Name Alternative
IY-81149 (sodium)
UNSPSC
12352005
Target
Proton Pump; TOPK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Membrane Transporter/Ion Channel
Applications
COVID-19-anti-virus
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ilaprazole-sodium.html
Purity
99.84
Solubility
DMSO : 41.67 mg/mL (ultrasonic)
Smiles
O=S(C1=NC2=CC=C(N3C=CC=C3)C=C2[N-]1)CC4=NC=CC(OC)=C4C.[Na+]
Molecular Formula
C19H17N4NaO2S
Molecular Weight
388.42
References & Citations
[1]Kwon D, et al. Effects of IY-81149, a newly developed proton pump inhibitor, on gastric acid secretion in vitro and in vivo. Arzneimittelforschung. 2001;51 (3) :204-213.|[2]Zheng M, et al. Proton pump inhibitor ilaprazole suppresses cancer growth by targeting T-cell-originated protein kinase. Oncotarget. 2017;8 (24) :39143-39153.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
Launched

Related Products

CatalogName
HY-101664-01Ilaprazole
HY-148051-01Ilaprazole sulfone
HY-101664R-01Ilaprazole (Standard)
HY-101664SIlaprazole-d3
HY-W791754Paeonolsilate (sodium)
HY-W272811Camphorsulfonate (sodium)
HY-W094710-01Sodium diacetate
HY-W050026APhenylacetylglutamine (sodium)
HY-W009640AMofebutazone (sodium)
HY-22274-01DMPG (sodium)

Alternative Products

CatalogName
C17629Ilaprazole sodium
M37158-01Ilaprazole sodium hydrate
RM-I120130-01Ilaprazole Impurity 30 (Ilaprazole Pyridine N-Oxide Sodium Salt) discontinued see RM-I120102
C6364-5Ilaprazole

Popular Products