RegisterLogin

Ilaprazole

CAT: 0804-HY-101664-01Size: 2 mgDry Ice: NoHazardous: No
CAT#:0804-HY-101664-01Size:2 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Ilaprazole (IY-81149) is an orally active proton pump inhibitor. Ilaprazole irreversibly inhibits H+/K+-ATPase in a dose-dependent manner with an IC50 of pump inhibitory activity of 6 μM in rabbit parietal cell preparation. Ilaprazole is used for the research of gastric ulcers. Ilaprazole is also a potent TOPK (T-lymphokine-activated killer cell-originated protein kinase) inhibitor[1][2].
CAS Number
[172152-36-2]
Product Name Alternative
IY-81149
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Proton Pump; TOPK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Membrane Transporter/Ion Channel
Applications
Cancer-programmed cell death
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Ilaprazole.html
Purity
99.97
Solubility
DMSO : ≥ 35 mg/mL|Ethanol : 5 mg/mL (ultrasonic)
Smiles
O=S(C1=NC2=CC=C(N3C=CC=C3)C=C2N1)CC4=NC=CC(OC)=C4C
Molecular Formula
C19H18N4O2S
Molecular Weight
366.44
Precautions
H302, H315, H319, H335
References & Citations
[1]Kwon D, et al. Effects of IY-81149, a newly developed proton pump inhibitor, on gastric acid secretion in vitro and in vivo. Arzneimittelforschung. 2001;51 (3) :204-13.|[2]Zheng M, et al. Proton pump inhibitor ilaprazole suppresses cancer growth by targeting T-cell-originated protein kinase. Oncotarget. 2017;8 (24) :39143-39153.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched

Related Products

CatalogName

Alternative Products

CatalogName
sc-488065Ilaprazole
TRC-M396308-25MGDesoxy Ilaprazole
sc-488066Ilaprazole-d3
A17277-5Ilaprazole 5mg
A17277-25Ilaprazole 25mg
A17277-500Ilaprazole 500mg
C17629Ilaprazole sodium
MBS5816578Ilaprazole sulfone
A17277-2Ilaprazole 2mg
A17277-50Ilaprazole 50mg

Popular Products