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Ilaprazole (Standard)

CAT: 0804-HY-101664R-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-101664R-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ilaprazole (Standard) is the analytical standard of Ilaprazole. This product is intended for research and analytical applications. Ilaprazole (IY-81149) is an orally active proton pump inhibitor. Ilaprazole irreversibly inhibits H+/K+-ATPase in a dose-dependent manner with an IC50 of pump inhibitory activity of 6 μM in rabbit parietal cell preparation. Ilaprazole is used for the research of gastric ulcers. Ilaprazole is also a potent TOPK (T-lymphokine-activated killer cell-originated protein kinase) inhibitor[1][2].
CAS Number
172152-36-2
Product Name Alternative
IY-81149 (Standard)
UNSPSC
12352005
Target
Proton Pump; Reference Standards; TOPK
Type
Reference Standards
Related Pathways
Cell Cycle/DNA Damage; Membrane Transporter/Ion Channel; Others
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ilaprazole-standard.html
Smiles
O=S(C1=NC2=CC=C(N3C=CC=C3)C=C2N1)CC4=NC=CC(OC)=C4C
Molecular Formula
C19H18N4O2S
Molecular Weight
366.44
References & Citations
[1]Kwon D, et al. Effects of IY-81149, a newly developed proton pump inhibitor, on gastric acid secretion in vitro and in vivo. Arzneimittelforschung. 2001;51 (3) :204-13.|[2]Zheng M, et al. Proton pump inhibitor ilaprazole suppresses cancer growth by targeting T-cell-originated protein kinase. Oncotarget. 2017;8 (24) :39143-39153.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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