Ilaprazole sulfone

• Description:

  Ilaprazole sulfone is the major metabolite of Ilaprazole (HY-101664), is predominantly catalysed by CYP3A4/5. Ilaprazole (IY-81149) is an orally active proton pump inhibitor[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H302-H315-H319

• Target:

  Drug Metabolite

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/ilaprazole-sulfone.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=S (C1=NC2=CC=C (N3C=CC=C3) C=C2N1) (CC4=NC=CC (OC) =C4C) =O

• Molecular Formula:

  C19H18N4O3S

• Molecular Weight:

  382.44

• Precautions:

  P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501

• References & Citations:

  [1]Seo KA, et al. Ilaprazole, a new proton pump inhibitor, is primarily metabolized to ilaprazole sulfone by CYP3A4 and 3A5. Xenobiotica. 2012 Mar;42 (3) :278-84.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  172152-37-3