CHK-IN-1

• UNSPSC Description:

  CHK-IN-1 is an inhibitor of CHK1 and CHK2, with anti-proliferative activities.

• Target Antigen:

  Checkpoint Kinase (Chk)

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/Thieno[2,3-d]pyridazine-7-carboxamide,_2-_3-fluorophenyl_-4-[_3S_-3-piperidinylamino]-,_hydrochloride.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=NN=C(N[C@@H]2CNCCC2)C3=C1SC(C4=CC=CC(F)=C4)=C3)N.[H]Cl

• Molecular Weight:

  407.89

• References & Citations:

  [1]Novel compounds and therapeutic use thereof for protein kinase inhibition. EP 2477496 A1

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1278405-51-8