CHK-IN-1

• Description :

  CHK-IN-1 is an inhibitor of CHK1 and CHK2, with anti-proliferative activities.

• UNSPSC :

  12352005

• Target :

  Checkpoint Kinase (Chk)

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/Thieno[2,3-d]pyridazine-7-carboxamide,_2-_3-fluorophenyl_-4-[_3S_-3-piperidinylamino]-,_hydrochloride.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C1=NN=C(N[C@@H]2CNCCC2)C3=C1SC(C4=CC=CC(F)=C4)=C3)N.[H]Cl

• Molecular Formula :

  C18H19ClFN5OS

• Molecular Weight :

  407.89

• References & Citations :

  [1]Novel compounds and therapeutic use thereof for protein kinase inhibition. EP 2477496 A1

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  Chk1; Chk2

• CAS Number :

  [1278405-51-8]