CHK-336

• Description :

  CHK-336 (Example 1) is an orally active LDHA inhibitor (IC50[1].

• UNSPSC :

  12352005

• Target :

  Lactate Dehydrogenase

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Metabolism-sugar/lipid metabolism

• Field of Research :

  Metabolic Disease

• Assay Protocol :

  https://www.medchemexpress.com/chk-336.html

• Purity :

  98.50

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  O=C(C1=CSC(N2N=C(C(CC3=CC=C(S(=O)(N)=O)C(F)=C3)=C2CC4CC4)C5=CC=C(F)C=C5)=N1)O

• Molecular Formula :

  C24H20F2N4O4S2

• Molecular Weight :

  530.57

• References & Citations :

  [1]David Andrew Powell, et al. Substituted pyrazolyl compounds and methods of use thereof. Patent WO2021234547A1.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light)

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 1

• Isoform :

  LDHA

• CAS Number :

  [2743436-86-2]