AZD 4407

• Description :

  AZD 4407 is a potent 5-lipoxygenase inhibitor.

• CAS Number :

  [166882-70-8]

• Product Name Alternative :

  ZD 4407

• UNSPSC :

  12352005

• Target :

  Lipoxygenase

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/AZD_4407.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C1N(C)C2=C(C=C(SC3=CC([C@]4(O)C[C@H](C)OCC4)=CS3)C=C2)C1

• Molecular Formula :

  C19H21NO3S2

• Molecular Weight :

  375.50

• References & Citations :

  [1]Jonathan Hutton, et al. Use of a Titanium Thienyl Anion and a Simple Procedure for Introducing a Thiol Group into Thiophene in the Development of a Manufacturing Route to the 5-Lipoxygenase Inhibitor ZD4407. Org Process Res Dev. 1997 Jan 15;1 (1) : 61–67.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  5-LOX