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Tigecycline (mesylate)

CAT: 0804-HY-B0117BSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-B0117BSize:1 Each
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Description
Tigecycline mesylate (GAR-936 mesylate) is a broad-spectrum glycylcycline antibiotic. The mean inhibitory concentration (MIC) of Tigecycline for E. coli (MG1655 strain) is approximately 125 ng/mL[1]. MIC50 and MIC90 are 1 and 2 mg/L for Acinetobacter baumannii (A. baumannii), respectively[2].
CAS Number
1135871-27-0
Product Name Alternative
GAR-936 mesylate
UNSPSC
12352005
Target
Antibiotic; Autophagy; Bacterial
Type
Reference compound
Related Pathways
Anti-infection; Autophagy
Applications
Cancer-programmed cell death
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/tigecycline-mesylate.html
Solubility
10 mM in DMSO
Smiles
O=C(C(C1=O)=C(O)[C@@H](N(C)C)[C@]2([H])C[C@]3([H])CC4=C(C(C3=C(O)[C@@]21O)=O)C(O)=C(NC(CNC(C)(C)C)=O)C=C4N(C)C)N.O=S(C)(O)=O
Molecular Formula
C30H43N5O11S
Molecular Weight
681.75
References & Citations
[1]Jitkova Y, et al. A novel formulation of tigecycline has enhanced stability and sustained antibacterial and antileukemic activity. PLoS One. 2014 May 28;9 (5) :e95281.|[2]Falagas ME, et al. Activity of TP-6076 against carbapenem-resistant Acinetobacter baumannii isolates collected from inpatients in Greek hospitals. Int J Antimicrob Agents. 2018 Aug;52 (2) :269-271.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched

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