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Tetrindole (mesylate)

CAT: 0804-HY-101169Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-101169Size:1 mg
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Description
Tetrindole mesylate is a selective inhibitor of monoamine oxidase A (MAO A) . Tetrindole mesylate inhibits rat brain mitochondrial MAO A in a competitive manner with a Ki value of 0.4 μM and inhibits MAO B with a Ki of 110 μM. Tetrindole mesylate has antidepressant activity[1][2].
CAS Number
170964-68-8
UNSPSC
12352005
Target
Monoamine Oxidase
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Purity
99.93
Solubility
10 mM in DMSO
Smiles
CS(=O)(O)=O.N12C3=C(C4=C1C(NCC2)CCC4)C=C(C5CCCCC5)C=C3
Molecular Formula
C21H30N2O3S
Molecular Weight
390.54
References & Citations
[1]A E Medvedev, et al. Monoamine oxidase inhibition by novel antidepressant tetrindole. Biochem Pharmacol. 1994 Jan 20;47 (2) :303-8.|[2]William D Gwynne, et al. Monoamine oxidase-A activity is required for clonal tumorsphere formation by human breast tumor cells. Cell Mol Biol Lett. 2019 Nov 12;24:59.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MAO-A

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