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T338C Src-IN-2

CAT: 0804-HY-16906-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-16906-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
T338C Src-IN-2 is a potent mutant c-Src T338C kinase inhibitor with IC50 of 317 nM; also inhibits T338C/V323A and T338C/V323S with IC50 of 57 nM/19 nM.
CAS Number
[1351927-00-8]
UNSPSC
12352005
Target
Src
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/T338C-Src-IN-2.html
Purity
98.41
Solubility
10 mM in DMSO
Smiles
NC1=C2C(N(C(C)C)N=C2CC3=CC(C(CF)=O)=CC=C3)=NC=N1
Molecular Formula
C17H18FN5O
Molecular Weight
327.36
References & Citations
[1]Garske AL, et al. Chemical genetic strategy for targeting protein kinases based on covalent complementarity. Proc Natl Acad Sci U S A. 2011 Sep 13;108 (37) :15046-52.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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