Src Inhibitor 4

• Description :

  Src Inhibitor 4 (Compound 18) is a derivative of KX-01 and an Src inhibitor. Src Inhibitor 4 can inhibit tumor cells, disrupt microtubules, and induce cell cycle arrest, apoptosis, and immunogenic cell death. After the introduction of phenolic or aniline functionality, Src Inhibitor 4 can serve as a payload attachment site for antibody-drug conjugates and has anti-tumor activity[1].

• UNSPSC :

  12352005

• Target :

  Apoptosis; Src

• Related Pathways :

  Apoptosis; Protein Tyrosine Kinase/RTK

• Field of Research :

  Cancer

• Smiles :

  O=C(C1=CC=CC=C1)N2CCN(CCOC3=CC=C(C4=CC=C(CC(NCC5=CC=CC=C5)=O)N=C4)C=C3)CC2

• Molecular Formula :

  C33H34N4O3

• Molecular Weight :

  534.65

• References & Citations :

  [1]Oh Y, et al. Synthesis and evaluation of KX-01 analogs with an exploration of linker attachment points for antibody-drug conjugates. Bioorg Med Chem Lett. 2025 Jan 27;120:130114.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported