Src Inhibitor 4

CAT: 0804-HY-170971Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-170971Size:1 Each
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Description
Src Inhibitor 4 (Compound 18) is a derivative of KX-01 and an Src inhibitor. Src Inhibitor 4 can inhibit tumor cells, disrupt microtubules, and induce cell cycle arrest, apoptosis, and immunogenic cell death. After the introduction of phenolic or aniline functionality, Src Inhibitor 4 can serve as a payload attachment site for antibody-drug conjugates and has anti-tumor activity[1].
UNSPSC
12352005
Target
Apoptosis; Src
Related Pathways
Apoptosis; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
O=C(C1=CC=CC=C1)N2CCN(CCOC3=CC=C(C4=CC=C(CC(NCC5=CC=CC=C5)=O)N=C4)C=C3)CC2
Molecular Formula
C33H34N4O3
Molecular Weight
534.65
References & Citations
[1]Oh Y, et al. Synthesis and evaluation of KX-01 analogs with an exploration of linker attachment points for antibody-drug conjugates. Bioorg Med Chem Lett. 2025 Jan 27;120:130114.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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