RORγt inverse agonist 23

RORγt inverse agonist 23

• CAS Number: 2230779-18-5
• UNSPSC Description: RORγt inverse agonist 23 is a potent, selective, and orally available novel retinoic acid receptor-related orphan receptor γt inverse agonist.
• Target Antigen: ROR
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/rorγt-inverse-agonist-23.html
• Solubility: DMSO : ≥ 100 mg/mL
• Smiles: OC1C2=C(C=CC(S(N(C3=CC=C(CC)C=C3)C4CCC4)(=O)=O)=C2)OC(C5CCOCC5)C1
• Molecular Weight: 471.61
• References & Citations: [1]Chen L, et al. Discovery of Chromane-6-Sulfonamide Derivative as a Potent, Selective, and Orally Available Novel Retinoic Acid Receptor-Related Orphan Receptor γt Inverse Agonist. J Med Chem. 2021 Nov 11;64(21):16106-16131.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported