RORγt inverse agonist 13
CAT:
804-HY-131338-02
Size:
50 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
RORγt inverse agonist 13
- CAS Number: 2170477-75-3
- UNSPSC Description: RORγt inverse agonist 13 (Compound 3i) is a potent, orally active and selective RORγt inverse agonist, with improved agent-like properties, with an IC50 of 63.8 nM[1].
- Target Antigen: ROR
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
- Field of Research: Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/rorγt-inverse-agonist-13.html
- Purity: 98.13
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: O=C(O)CC1=CC=C(CNC(NC2=CC(Cl)=C(C3=CC=CC=C3OC(F)(F)F)C(Cl)=C2)=O)C=C1
- Molecular Weight: 513.29
- References & Citations: [1]Nannan Sun, et al. Discovery of carboxyl-containing biaryl ureas as potent RORγt inverse agonists. Eur J Med Chem. 2020 Jul 5;202:112536.
- Shipping Conditions: Blue Ice
- Storage Conditions: -20°C, 3 years (Powder)
- Clinical Information: No Development Reported