RORγt Inverse agonist 6
CAT:
804-HY-130243-06
Size:
100 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
RORγt Inverse agonist 6
- CAS Number: 1887161-80-9
- UNSPSC Description: RORγt Inverse agonist 6 (compound 43) is a RORγt inverse agonist for the study of Th17-driven autoimmune diseases. RORγt Inverse agonist 6 (compound 43) suppresses IL-17A gene expression by IL-23 stimulation in vivo[1].
- Target Antigen: ROR
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
- Field of Research: Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/ror-gamma-t-inverse-agonist-6.html
- Purity: 98.97
- Solubility: DMSO : 50 mg/mL (ultrasonic)
- Smiles: O=C([C@H]1CN(C(NC2=CC3=C(N(C(C)C)C(N(CC4CC4)C3=O)=O)C=C2)=O)CCO1)NC5=CC=C(C#N)C(Cl)=C5
- Molecular Weight: 565.02
- References & Citations: [1]Sato A, et al. Design and Synthesis of Conformationally Constrained RORγt Inverse Agonists. ChemMedChem. 2019 Oct 28.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported