LM-1484

• Description:

  LM-1484 is an antagonist of CysLT1 receptor and displays a higher affinity for 3H-LTC4 sites.

• UNSPSC:

  12352005

• Target:

  Leukotriene Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/LM-1484.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1C=C(C2=NN=NN2)OC3=C(/C=C/C4=CC=C(OCCCCC5=CC=CC=C5)C=C4)C=CC=C13

• Molecular Formula:

  C28H24N4O3

• Molecular Weight:

  464.52

• References & Citations:

  [1]Ravasi S, et al. Pharmacological differences among CysLT (1) receptor antagonists with respect to LTC (4) and LTD (4) in human lung parenchyma. Biochem Pharmacol. 2002 Apr 15;63 (8) :1537-46.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  LTC4/CysLT2; LTD4/CysLT1

• CAS Number:

  [197506-02-8]