G244-LM

• UNSPSC Description:

  G244-LM is a potent and specific inhibitor of tankyrase 1/2 that inhibits Wnt signaling[1].

• Target Antigen:

  PARP

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage;Epigenetics

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/g244-lm.html

• Purity:

  98.88

• Solubility:

  DMSO : 6.25 mg/mL (ultrasonic;warming;heat to 80°C)

• Smiles:

  O=C1C(CSCC2)=C2N=C(N3CCN(C4=CC=CC=C4S(=O)(C)=O)CC3)N1

• Molecular Weight:

  406.52

• References & Citations:

  [1]Lau T, et al. A novel tankyrase small-molecule inhibitor suppresses APC mutation-driven colorectal tumor growth. Cancer Res. 2013 May 15;73(10):3132-44.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Clinical Information:

  No Development Reported

• CAS Number:

  1563007-08-8