G244-LM

CAT: 0804-HY-117705-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-117705-01Size:5 mg
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Description
G244-LM is a potent and specific inhibitor of tankyrase 1/2 that inhibits Wnt signaling[1].
CAS Number
[1563007-08-8]
UNSPSC
12352005
Target
PARP; Wnt
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics; Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/g244-lm.html
Purity
98.32
Solubility
DMSO : 6.25 mg/mL (ultrasonic; warming; heat to 80°C)
Smiles
O=C1C(CSCC2)=C2N=C(N3CCN(C4=CC=CC=C4S(=O)(C)=O)CC3)N1
Molecular Formula
C18H22N4O3S2
Molecular Weight
406.52
References & Citations
[1]Lau T, et al. A novel tankyrase small-molecule inhibitor suppresses APC mutation-driven colorectal tumor growth. Cancer Res. 2013 May 15;73 (10) :3132-44.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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