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LY 178002

CAT: 0804-HY-101579-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-101579-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LY 178002 is a potent inhibitor of 5-lipoxygenase (5-LPO), phospholipase A2, with IC50 of 0.6 μM for 5-lipoxygenase, inhibits cellular production of LTB4 by human polymorphonuclear leukocytes, and shows relatively weak inhibition on cyclooxygenase.
CAS Number
107889-32-7
UNSPSC
12352005
Target
COX; Lipoxygenase; Phospholipase
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/LY_178002.html
Solubility
10 mM in DMSO
Smiles
O=C1NCS/C1=C/C2=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C2
Molecular Formula
C18H25NO2S
Molecular Weight
319.46
References & Citations
[1]Panetta JA, et al. The anti-inflammatory effects of LY178002 and LY256548. Agents Actions. 1989 Jun;27 (3-4) :300-2.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-LOX; COX; Phospholipase A

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CatalogName
T15825-01LY 178002
A19333-50LY 178002 50mg
A19333-10LY 178002 10mg
A19333-5LY 178002 5mg
A19333-100LY 178002 100mg
A19333-25LY 178002 25mg
A19333-1LY 178002 1mg

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