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LY-426965

CAT: 0804-HY-117799Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-117799Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LY426965 is a potent arylpiperazine compound known for its role as a full antagonist of the serotonin 1A receptor, lacking partial agonist activity. It is identified as a selective 5-HT1A antagonist, showing promise in preclinical studies for treating conditions associated with serotonin dysregulation, such as smoking cessation and depression-related disorders[1].
CAS Number
228418-82-4
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/ly-426965.html
Smiles
O=C([C@@](C)(CCN1CCN(CC1)C2=CC=CC=C2OC)C3=CC=CC=C3)C4CCCCC4
Molecular Formula
C28H38N2O2
Molecular Weight
434.61
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Asymmetric Construction of Quaternary Centers by Enantioselective Allylation: Application to the Synthesis of the Serotonin Antagonist LY426965
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT1 Receptor