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PD 127443

CAT: 0804-HY-123391Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-123391Size:1 Each
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Description
PD 127443 is an inhibitor of 5-lipoxygenase and cyclooxygenase. PD 127443 has anti-inflammatory activity[1].
CAS Number
121502-05-4
UNSPSC
12352005
Target
COX; Lipoxygenase
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/pd-127443.html
Smiles
OC1=C(C=C(C=C1C(C)(C)C)/C=C/C2=NNC(C)=C2)C(C)(C)C
Molecular Formula
C20H28N2O
Molecular Weight
312.45
References & Citations
[1]Schrier DJ, et al. The in vivo antiinflammatory effects of (E) -2,6-bis (1,1-dimethyl-ethyl) -4-[2- (5-methyl-1H-pyrazol-3-yl) ethenyl ] phenol (PD 127443) a novel dual inhibitor of 5-lipoxygenase and cyclooxygenase. Agents Actions. 1989 Jun;27 (3-4) :391-4.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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