EEF2K (Phospho-Ser366) Colorimetric Cell-Based ELISA Kit

• Description:

  The eEF2K (Phospho-Ser366) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor eEF2K (Phospho-Ser366) protein expression profile in cells. The kit can be used for measuring the relative amounts of eEF2K (Phospho-Ser366) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on eEF2K (Phospho-Ser366) .

• Synonyms:

  Calcium/calmodulin-dependent eukaryotic elongation factor-2 kinase; EF2K; Elongation factor 2 kinase; eEF-2 kinase; eEF-2K; kinase eEF2K

• Gene Name:

  EEF2K

• UniProt:

  O00418

• Reactivity:

  Human, Rat

• Applications:

  ELISA

• Sample Type:

  Cell lines

• Detection Range:

  > 5000 cells/well

• Function:

  Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive. In turn, the rate of protein synthesis is reduced.

• Molecular Weight:

  82144 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  Eukaryotic elongation factor 2 kinase