Products for Research Use Only
RegisterLogin

Anti-Phospho-eEF2k (Ser366) Antibody

CAT: 0519-M02277-200ulSize: 200 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0519-M02277-200ulSize:200 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive. In turn, the rate of protein synthesis is reduced.
Description
Boster Bio Anti-Phospho-eEF2k (Ser366) Antibody (Catalog # M02277) . Tested in WB application (s) . This antibody reacts with Human.
Synonyms
Eukaryotic elongation factor 2 kinase, eEF-2 kinase, eEF-2K, 2.7.11.20, Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase, EEF2K
Gene Name
EEF2K
UniProt
O00418
Host
Rabbit
Reactivity
Human
Immunogen
This Phospho-eEF2k (Ser366) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 337-371 amino acids from the human region of human EEF2k.
Clonality
Polyclonal
Applications
WB
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive. In turn, the rate of protein synthesis is reduced.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
82144 Da
Applications Notes
WB: 1:500
Isotype
Rabbit IgG
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

UniProtKB · O00418

Eukaryotic elongation factor 2 kinase

EF2K_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O00418
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
EEF2K
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
eEF-2 kinase, eEF-2K
EC number
2.7.11.20
Processing
—
Secondary accessions
Q8N588
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Ligand

ATP-bindingCalciumNucleotide-binding

Molecular function

Calmodulin-bindingKinaseSerine/threonine-protein kinaseTransferase

Related Products

CatalogName
EKC1986EEF2K (Phospho-Ser366) Colorimetric Cell-Based ELISA Kit
A02277S359Anti-Phospho-eEF2K (S359) Antibody
A02277S366-1Anti-eEF2K (phospho-S366) Antibody
A02277S366-2Anti-Phospho-eEF2K (S366) Antibody
A02277-1Anti-eEF2K Antibody
A02277Anti-eEF2K Antibody
A02277-3Anti-EEF2K Antibody Picoband®
A02277-2Anti-eEF2K (P360) Antibody
M02277-1Anti-EEF2K Antibody (Monoclonal, 34E38)
A02277-3-APCAnti-EEF2K Antibody Picoband®, APC Conjugate

Alternative Products

CatalogName
MBS9600668-01Phospho-eEF2k (Ser366) Antibody
OASG02324-100ULEEF2K Antibody (Phospho-Ser366)
MBS9502377-01eEF2K (Phospho-Ser366) Antibody
A0071-01eEF2K (phospho Ser366) Antibody
ABF3573Phospho-eEF2k (Ser366) Antibody
A1947-100Phospho EEF2K (Ser366) Antibody
TMAC-01233-01Anti-Phospho-eEF2K (Ser366) Polyclonal Antibody
MBS8520373-01eEF2K (phospho Ser366) Polyclonal Antibody
MBS8585494-01eEF2K (Phospho-Ser366) Polyclonal Antibody
RD85985A-01Phospho-EEF2K (Ser366) Polyclonal Antibody

Popular Products