SSB (Phospho-Ser366) Colorimetric Cell-Based ELISA Kit

• Description:

  The SSB (Phospho-Ser366) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor SSB (Phospho-Ser366) protein expression profile in cells. The kit can be used for measuring the relative amounts of SSB (Phospho-Ser366) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on SSB (Phospho-Ser366) .

• Synonyms:

  Lupus La protein; Sjoegren syndrome type B antigen; SS-B; La ribonucleoprotein; La autoantigen

• Gene Name:

  SSB

• UniProt:

  P05455

• Reactivity:

  Human

• Applications:

  ELISA

• Sample Type:

  Cell lines

• Detection Range:

  > 5000 cells/well

• Function:

  Binds to the 3' poly (U) terminus of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation (PubMed:3192525, PubMed:2470590) . In case of Coxsackievirus B3 infection, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation (PubMed:12384597) .

• Molecular Weight:

  46837 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  Lupus La protein

• Subcellular Location:

  Nucleus.