CaMK2 beta/gamma Colorimetric Cell-Based ELISA

• Description:

  The CaMK2 beta/gamma Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor CaMK2 beta/gamma protein expression profile in cells. The kit can be used for measuring the relative amounts of CaMK2 beta/gamma in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on CaMK2 beta/gamma.

• Synonyms:

  Calcium/calmodulin-dependent protein kinase type II subunit gamma; CaM kinase II subunit gamma; CaMK-II subunit gamma;2.7.11.17; CAMK2G; CAMK, CAMK-II, CAMKG

• Gene Name:

  CAMK2G

• UniProt:

  Q13555

• Reactivity:

  Human, Mouse, Rat

• Tissue Specificity:

  Expressed in skeletal muscle.

• Applications:

  ELISA

• Detection Range:

  > 5000 cells/well

• Function:

  Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca (2+) /calmodulin-binding and autophosphorylation, and is involved in sarcoplasmic reticulum Ca (2+) transport in skeletal muscle and may function in dendritic spine and synapse formation and neuronal plasticity. In slow- twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca (2+) transport and in fast-twitch muscle participates in the control of Ca (2+) release from the SR through phosphorylation of the ryanodine receptor-coupling factor triadin. In neurons, may participate in the promotion of dendritic spine and synapse formation and maintenance of synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning.

• Molecular Weight:

  62607 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  Calcium/calmodulin-dependent protein kinase type II subunit gamma

• Subcellular Location:

  Sarcoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side.