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GAS41 Colorimetric Cell-Based ELISA

CAT: 0519-EKC1663Size: 1 Kit, containing one 96 Well Plate and all necessary reagentsDry Ice: NoHazardous: No
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CAT#:0519-EKC1663Size:1 Kit, containing one 96 Well Plate and all necessary reagents
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The GAS41 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor GAS41 protein expression profile in cells. The kit can be used for measuring the relative amounts of GAS41 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on GAS41.
Synonyms
YEATS domain-containing protein 4; Glioma-amplified sequence 41; Gas41; NuMA-binding protein 1; NuBI-1; NuBI1; YEATS4; GAS41
Gene Name
YEATS4
UniProt
O95619
Reactivity
Human, Mouse
Tissue Specificity
Expressed in brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle.
Applications
ELISA
Detection Range
> 5000 cells/well
Function
Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage.
Molecular Weight
26499 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
YEATS domain-containing protein 4
Subcellular Location
Nucleus.

UniProtKB · O95619

YEATS domain-containing protein 4

YETS4_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O95619
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
YEATS4
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q9NQD0
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Molecular function

Chromatin regulator

Domain

Coiled coil

Biological process

Growth regulationTranscriptionTranscription regulation

PTM

Isopeptide bondUbl conjugation

Cellular component

Nucleus

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