KLF11 Colorimetric Cell-Based ELISA

• Description:

  The KLF11 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor KLF11 protein expression profile in cells. The kit can be used for measuring the relative amounts of KLF11 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on KLF11.

• Synonyms:

  Krueppel-like factor 11; Transforming growth factor-beta-inducible early growth response protein 2; TGFB-inducible early growth response protein 2; TIEG-2; KLF11; FKLF, TIEG2

• Gene Name:

  KLF11

• UniProt:

  O14901

• Reactivity:

  Human, Mouse

• Tissue Specificity:

  Ubiquitous. Higher expression in erythroid cells.

• Applications:

  ELISA

• Detection Range:

  > 5000 cells/well

• Function:

  Transcription factor (PubMed:9748269, PubMed:10207080) . Activates the epsilon- and gamma-globin gene promoters and, to a much lower degree, the beta-globin gene and represses promoters containing SP1-like binding inhibiting cell growth (PubMed:9748269, PubMed:10207080, PubMed:16131492) . Represses transcription of SMAD7 which enhances TGF-beta signaling (By similarity) . Induces apoptosis (By similarity) .

• Molecular Weight:

  55139 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  Krueppel-like factor 11

• Subcellular Location:

  Nucleus.