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UBF1 Colorimetric Cell-Based ELISA Kit

CAT: 0519-EKC1586Size: 1 Kit, containing one 96 Well Plate and all necessary reagentsDry Ice: NoHazardous: No
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CAT#:0519-EKC1586Size:1 Kit, containing one 96 Well Plate and all necessary reagents
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The UBF1 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor UBF1 protein expression profile in cells. The kit can be used for measuring the relative amounts of UBF1 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on UBF1.
Synonyms
Nucleolar transcription factor 1; Autoantigen NOR-90; Upstream-binding factor 1; UBF-1; UBTF; UBF, UBF1
Gene Name
UBTF
UniProt
P17480
Reactivity
Human, Mouse, Rat
Applications
ELISA
Detection Range
> 5000 cells/well
Function
Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element.
Molecular Weight
89406 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Nucleolar transcription factor 1
Subcellular Location
Nucleus, nucleolus.

UniProtKB · P17480

Nucleolar transcription factor 1

UBF1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P17480
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
UBTF
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A8K6R8
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Molecular function

ActivatorDNA-binding

Coding sequence diversity

Alternative splicing

Disease

Disease variantIntellectual disabilityNeurodegeneration

Cellular component

Nucleus

Domain

Repeat

Biological process

TranscriptionTranscription regulation

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