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Synuclein Colorimetric Cell-Based ELISA Kit

CAT: 0519-EKC1557Size: 1 Kit, containing one 96 Well Plate and all necessary reagentsDry Ice: NoHazardous: No
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CAT#:0519-EKC1557Size:1 Kit, containing one 96 Well Plate and all necessary reagents
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The Synuclein Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Synuclein protein expression profile in cells. The kit can be used for measuring the relative amounts of Synuclein in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Synuclein.
Synonyms
Alpha-synuclein; Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor; NACP; SNCA; NACP, PARK1
Gene Name
SNCA
UniProt
P37840
Reactivity
Human, Mouse, Rat
Tissue Specificity
Expressed principally in brain but is also expressed in low concentrations in all tissues examined except in liver. Concentrated in presynaptic nerve terminals.
Applications
ELISA
Detection Range
> 5000 cells/well
Function
May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.
Molecular Weight
14460 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Alpha-synuclein
Subcellular Location
Cytoplasm, cytosol. Membrane. Nucleus. Cell junction, synapse. Secreted. Membrane-bound in dopaminergic neurons.

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