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SPHK2 Colorimetric Cell-Based ELISA Kit

CAT: 0519-EKC1536Size: 1 Kit, containing one 96 Well Plate and all necessary reagentsDry Ice: NoHazardous: No
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CAT#:0519-EKC1536Size:1 Kit, containing one 96 Well Plate and all necessary reagents
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The SPHK2 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor SPHK2 protein expression profile in cells. The kit can be used for measuring the relative amounts of SPHK2 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on SPHK2.
Synonyms
Sphingosine kinase 2; SK 2; SPK 2;2.7.1.91 ; SPHK2
Gene Name
SPHK2
UniProt
Q9NRA0
Reactivity
Human, Mouse, Rat
Applications
ELISA
Detection Range
> 5000 cells/well
Function
Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. Also acts on D-erythro- dihydrosphingosine, D-erythro-sphingosine and L-threo- dihydrosphingosine. Binds phosphoinositides.
Molecular Weight
69217 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Sphingosine kinase 2
Subcellular Location
Isoform 1: Cytoplasm. Membrane.

UniProtKB · Q9NRA0

Sphingosine kinase 2

SPHK2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9NRA0
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SPHK2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
SK 2, SPK 2
EC number
2.7.1.91
Processing
—
Secondary accessions
A0T4C8, B4DU87, Q9BRN1, Q9H0Q2, Q9NWU7
Protein keywords

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingNucleotide-binding

Cellular component

CytoplasmEndoplasmic reticulumLysosomeMembraneMitochondrionMitochondrion inner membraneNucleus

Molecular function

KinaseTransferase

Biological process

Lipid metabolism

PTM

Phosphoprotein

Technical term

Proteomics identificationReference proteome

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