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Paxillin Colorimetric Cell-Based ELISA Kit

CAT: 0519-EKC1443Size: 1 Kit, containing one 96 Well Plate and all necessary reagentsDry Ice: NoHazardous: No
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CAT#:0519-EKC1443Size:1 Kit, containing one 96 Well Plate and all necessary reagents
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The Paxillin Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Paxillin protein expression profile in cells. The kit can be used for measuring the relative amounts of Paxillin in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Paxillin.
Synonyms
Paxillin; PXN
Gene Name
PXN
UniProt
P49023
Reactivity
Human, Mouse, Rat
Applications
ELISA
Detection Range
> 5000 cells/well
Function
Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion) .
Molecular Weight
64505 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Paxillin
Subcellular Location
Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Cytoplasm, cell cortex. Colocalizes with integrins at the cell periphery. Colocalize with PXN to membrane ruffles and the leading edge of migrating cells (PubMed:23128389) .

UniProtKB · P49023

Paxillin

PAXI_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P49023
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PXN
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B2RAI3, B7ZMB4, O14970, O14971, O60360, Q5HYA4
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Biological process

Cell adhesion

Cellular component

Cell junctionCytoplasmCytoskeleton

Domain

LIM domainRepeat

Ligand

Metal-bindingZinc

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