NudC Colorimetric Cell-Based ELISA Kit

• Description:

  The NudC Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor NudC protein expression profile in cells. The kit can be used for measuring the relative amounts of NudC in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on NudC.

• Synonyms:

  Nuclear migration protein nudC; Nuclear distribution protein C homolog; NUDC

• Gene Name:

  NUDC

• UniProt:

  Q9Y266

• Reactivity:

  Human, Mouse, Rat

• Tissue Specificity:

  Ubiquitous. Highly expressed in fetal liver, kidney, lung and brain. Highly expressed in adult pancreas, kidney, skeletal muscle, liver, lung, placenta, prostate, brain and heart.

• Applications:

  ELISA

• Detection Range:

  > 5000 cells/well

• Function:

  Plays a role in neurogenesis and neuronal migration (By similarity) . Necessary for correct formation of mitotic spindles and chromosome separation during mitosis. Necessary for cytokinesis and cell proliferation.

• Molecular Weight:

  38243 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  Nuclear migration protein nudC

• Subcellular Location:

  Cytoplasm, cytoskeleton. Nucleus. In a filamentous pattern adjacent to the nucleus of migrating cerebellar granule cells. Colocalizes with tubulin and dynein and with the microtubule organizing center. Distributed throughout the cytoplasm of non-migrating cells. A small proportion is nuclear, in a punctate pattern.