DAPP1 Colorimetric Cell-Based ELISA Kit

• Description:

  The DAPP1 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor DAPP1 protein expression profile in cells. The kit can be used for measuring the relative amounts of DAPP1 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on DAPP1.

• Synonyms:

  3' phosphoinositide-interacting SH2 domain containing protein; B lymphocyte adapter protein BAM32; Bam32; Dual adaptor for phosphotyrosine and 3-phosphoinositides 1; PHISH; dual adapter for phosphotyrosine and 3-phosphoinositides

• Gene Name:

  DAPP1

• UniProt:

  Q9UN19

• Reactivity:

  Human, Mouse

• Tissue Specificity:

  Highly expressed in placenta and lung, followed by brain, heart, kidney, liver, pancreas and skeletal muscle. Expressed by B-lymphocytes, but not T-lymphocytes or nonhematopoietic cells.

• Applications:

  ELISA

• Sample Type:

  Cell lines

• Detection Range:

  > 5000 cells/well

• Function:

  May act as a B-cell-associated adapter that regulates B- cell antigen receptor (BCR) -signaling downstream of PI3K.

• Molecular Weight:

  32194 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide

• Subcellular Location:

  Cytoplasm. Membrane; Peripheral membrane protein. Membrane-associated after cell stimulation leading to its translocation.