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MCL1 Colorimetric Cell-Based ELISA Kit

CAT: 0519-EKC1353Size: 1 Kit, containing one 96 Well Plate and all necessary reagentsDry Ice: NoHazardous: No
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CAT#:0519-EKC1353Size:1 Kit, containing one 96 Well Plate and all necessary reagents
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The MCL1 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor MCL1 protein expression profile in cells. The kit can be used for measuring the relative amounts of MCL1 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on MCL1.
Synonyms
Bcl-2-related protein EAT/mcl1; EAT/MCL-1; induced myeloid leukemia cell differentiation protein Mcl-1; mcl1/EAT; myeloid cell leukemia sequence 1
Gene Name
MCL1
UniProt
Q07820
Reactivity
Human, Mouse, Rat
Applications
ELISA
Sample Type
Cell lines
Detection Range
> 5000 cells/well
Function
Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.
Molecular Weight
37337 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Induced myeloid leukemia cell differentiation protein Mcl-1
Subcellular Location
Membrane; Single-pass membrane protein. Cytoplasm. Mitochondrion. Nucleus, nucleoplasm. Cytoplasmic, associated with mitochondria.

UniProtKB · Q07820

Induced myeloid leukemia cell differentiation protein Mcl-1

MCL1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q07820
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MCL1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B2R6B2, D3DV03, D3DV04, Q9HD91, Q9NRQ3, Q9NRQ4, Q9UHR7, Q9UHR8, Q9UHR9, Q9UNJ1
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

ApoptosisDifferentiation

Cellular component

CytoplasmMembraneMitochondrionNucleus

Molecular function

Developmental protein

PTM

Isopeptide bondPhosphoproteinUbl conjugation

Domain

TransmembraneTransmembrane helix

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