BCAR1 Colorimetric Cell-Based ELISA Kit

• Description:

  The BCAR1 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor BCAR1 protein expression profile in cells. The kit can be used for measuring the relative amounts of BCAR1 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on BCAR1.

• Synonyms:

  BCA1; BCAR1; Breast cancer anti-estrogen resistance 1 protein; CAS; CRK-associated substrate; CRKAS

• Gene Name:

  BCAR1

• UniProt:

  P56945

• Reactivity:

  Human, Mouse, Rat

• Tissue Specificity:

  Widely expressed with an abundant expression in the testis. Low level of expression seen in the liver, thymus, and peripheral blood leukocytes. The protein has been detected in a B-cell line.

• Applications:

  ELISA

• Sample Type:

  Cell lines

• Detection Range:

  > 5000 cells/well

• Function:

  Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion. Implicated in induction of cell migration. Overexpression confers antiestrogen resistance on breast cancer cells.

• Molecular Weight:

  93372 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  Breast cancer anti-estrogen resistance protein 1

• Subcellular Location:

  Cell junction, focal adhesion. Cytoplasm. Unphosphorylated form localizes in the cytoplasm and can move to the membrane upon tyrosine phosphorylation.