TMPRSS3 Colorimetric Cell-Based ELISA

• Description:

  The TMPRSS3 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor TMPRSS3 protein expression profile in cells. The kit can be used for measuring the relative amounts of TMPRSS3 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on TMPRSS3.

• Synonyms:

  Transmembrane protease serine 3;3.4.21.-; Serine protease TADG-12; Tumor-associated differentially-expressed gene 12 protein; TMPRSS3; ECHOS1, TADG12; UNQ323/PRO382

• Gene Name:

  TMPRSS3

• UniProt:

  P57727

• Reactivity:

  Human, Mouse

• Tissue Specificity:

  Expressed in many tissues including fetal cochlea. Isoform T is found at increased levels in some carcinomas.

• Applications:

  ELISA

• Detection Range:

  > 5000 cells/well

• Function:

  Probable serine protease that plays a role in hearing. Acts as a permissive factor for cochlear hair cell survival and activation at the onset of hearing and is required for saccular hair cell survival (By similarity) . Activates ENaC (in vitro) .

• Molecular Weight:

  49405 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  Transmembrane protease serine 3

• Subcellular Location:

  Endoplasmic reticulum membrane; Single-pass type II membrane protein.