TMPRSS3 Colorimetric Cell-Based ELISA

CAT: 0519-EKC1757Size: 1 Kit - Containing One 96 Well Plate & All Necessary ReagentsDry Ice: NoHazardous: No
CAT#:0519-EKC1757Size:1 Kit - Containing One 96 Well Plate & All Necessary Reagents
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The TMPRSS3 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor TMPRSS3 protein expression profile in cells. The kit can be used for measuring the relative amounts of TMPRSS3 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on TMPRSS3.
Synonyms
Transmembrane protease serine 3;3.4.21.-; Serine protease TADG-12; Tumor-associated differentially-expressed gene 12 protein; TMPRSS3; ECHOS1, TADG12; UNQ323/PRO382
Gene Name
TMPRSS3
UniProt
P57727
Reactivity
Human, Mouse
Tissue Specificity
Expressed in many tissues including fetal cochlea. Isoform T is found at increased levels in some carcinomas.
Applications
ELISA
Detection Range
> 5000 cells/well
Function
Probable serine protease that plays a role in hearing. Acts as a permissive factor for cochlear hair cell survival and activation at the onset of hearing and is required for saccular hair cell survival (By similarity) . Activates ENaC (in vitro) .
Molecular Weight
49405 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Transmembrane protease serine 3
Subcellular Location
Endoplasmic reticulum membrane; Single-pass type II membrane protein.

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