ATF1 Colorimetric Cell-Based ELISA Kit

• Description:

  The ATF1 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor ATF1 protein expression profile in cells. The kit can be used for measuring the relative amounts of ATF1 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on ATF1.

• Synonyms:

  ATF1; Activating transcription factor 1; Cyclic-AMP-dependent transcription factor ATF-1; TCR-ATF1; TREB36 protein

• Gene Name:

  ATF1

• UniProt:

  P18846

• Reactivity:

  Human, Mouse, Rat

• Applications:

  ELISA

• Sample Type:

  Cell lines

• Detection Range:

  > 5000 cells/well

• Function:

  This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation.

• Molecular Weight:

  29233 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  Cyclic AMP-dependent transcription factor ATF-1

• Subcellular Location:

  Nucleus.