SDH-IN-14

• Description:

  SDH-IN-14 (Compound Z2) is an inhibitor of succinate dehydrogenase (SDH) . SDH-IN-14 has antifungal activity (EC50=2.7 μg/mL) against B.cinerea. SDH-IN-14 acts by disrupting the integrity of the cell wall and cell membrane[1].

• UNSPSC:

  12352005

• Target:

  Fungal; Succinate Dehydrogenase

• Type:

  Reference compound

• Related Pathways:

  Anti-infection; Metabolic Enzyme/Protease

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/sdh-in-14.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(NC1=NN=C(SCC(O)CN2C=CC3=C2C=CC=C3)S1)C4=CC=CC=C4C

• Molecular Formula:

  C21H20N4O2S2

• Molecular Weight:

  424.54

• References & Citations:

  [1]He B, et al. Antifungal Activity of Novel Indole Derivatives Containing 1,3,4-Thiadiazole. J Agric Food Chem. 2024 May 8;72 (18) :10227-10235.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported