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Pentosidine (TFA)

CAT: 0804-HY-113033ASize: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-113033ASize:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Pentosidine TFA is an advanced glycation end product (AGE) and cross-linked substance with fluorescent properties. Pentosidine TFA is present in various human tissues and can serve as a biomarker for diabetes, aging, uremia, protein accumulation damage, and non-enzymatic modification of long-lived proteins in the Maillard reaction. It aids in gaining a deeper understanding of the overall role of the Maillard reaction in aging and disease[1][2].
CAS Number
225784-09-8
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Neuroscience-Neurodegeneration
Field of Research
Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pentosidine-tfa.html
Solubility
10 mM in DMSO
Smiles
OC(C(F)(F)F)=O.OC([C@@H](N)CCCCN1C2=NC(NCCC[C@H](N)C(O)=O)=NC2=CC=C1)=O
Molecular Formula
C19H27F3N6O6
Molecular Weight
492.45
References & Citations
[1]Requena JR, et al. Measurement of pentosidine in biological samples. Methods Mol Med. 2000;38:209-17. |[2]Sell DR, et al. Pentosidine: a molecular marker for the cumulative damage to proteins in diabetes, aging, and uremia. Diabetes Metab Rev. 1991;7 (4) :239-251.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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